【个人简介】

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  Dr. Jing Chen (陈静) Associate Professer (副研究员)   Address: #345 the New Chemistry bldg，27 Shanda Nanlu, Jinan 250100, China (化学新楼345） Email: jingchen@sdu.edu.cn TeL: 0531-88363058

  
  

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【学习及工作经历】

2016-今  山东大学 化学与化工学院 分析化学 副研究员
2015-2016 大连医科大学 检验医学院 副教授
2011-2014 The Pennsylvania State University, post-doctoral fellow
2005-2011 中国科学院大连化学物理研究所 分析化学 博士
2001-2005 南京大学 学士

【主讲课程】

【研究领域和兴趣】

• 主要研究方向为纳米分析化学，包括基于新型纳米材料的环境、蛋白质/代谢组学样品预处理研究，色谱质谱新技术新方法开发等。欢迎对色谱质谱分析、环境分析感兴趣的同学报考我的硕士研究生，同时欢迎本科同学加入我们的研究团队。

【主要论著】

• 28.    Jing Chen*, Julia  D. Fine, Christopher A. Mullin; Are organosilicon safe for bee or humans? Sci. Total Environ. 2018, 612, 415-421. 
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• 27.    Ying Zhou, Jing Chen, Zhen Wang, Hui Liu*; Evaluating the risk of tumors diseases based on measurement of urinary and serumal antioxidants using the new agar diffusion methods. Oxid. Med. Cell. Longevi. 2017. 2017:6578453.
  
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• 26.   Christopher A. Mullin*, Jing Chen, Julia D. Fine, Maryann T. Frazier, James L. Frazier; The formulation makes the honey bee poison. Pest. Biochem. Phys. 2015, 120. 27-35
  
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• 25.   Jing Chen, Christopher A. Mullin*; Characterization of Trisiloxane Surfactants from Agrochemical Adjuvants and Pollinator-Related Matrices Using Liquid Chromatography Coupled to Mass Spectrometry. J. Agri. Food Chem., 2015, 3. 5210-5215. 
  
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• 24. Jing Chen*, Christopher A Mullin; Determination of Nonylphenol Ethoxylate and Octylphenol Ethoxylate Surfactants in Beehive Samples by High Performance Liquid Chromatography Coupled to Mass Spectrometry. Food Chem., 2014, 158. 473-479. 
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• 23. Jing Chen, Christopher A Mullin*; Quantitative Determination of Trisiloxane Surfactants in Beehive Environments Based on Liquid Chromatography Coupled to Mass Spectrometry. Environ. Sci. Tech. 2013, 47. 9317-9323
• This article was reported as “The decline in bees: Are pesticide surfactants to blame?” by separationsNOW.com,  John Wiley & Sons, Ltd.
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• 22. Jing Chen, Lina Zhou, Xiaoyan Zhang, Xin Lu, Rui Cao, Congjian Xu, Guowang Xu; Urinary Hydrophilic and Hydrophobic Metabolic Profiling Based on Liquid Chromatography-Mass Spectrometry Methods: Differential Metabolite Discovery Specific to Ovarian Cancer. Electrophoresis 2012, 33. 3361-3369. 

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• 21. Jing Chen, Xiaoyan Zhang, Rui Cao, Xin Lu, Sumin Zhao, Agnes Fekete, Qiang Huang, Philippe Schmitt-Kopplin, Yisheng Wang, Zhiliang Xu, Xiaoping Wan, Xiaohua Wu, Naiqing Zhao, Congjian Xu, Guowang Xu*; Serum 27-nor-5 beta-Cholestane-3,7,12,24,25 Pentol Glucuronide Discovered by Metabolomics as Potential Diagnostic Biomarker for Epithelium Ovarian Cancer. J. Proteom. Res. 2011, 10. 2625-2632. 

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• 20. Jing Chen, Yang Zhang, Xiaoyan Zhang, Rui Cao, Shili Chen, Qiang Huang, Xin Lu, Xiaoping Wan, Xiaohua Wu, Congjian Xu, Guowang Xu*; Application of L-EDA in Metabonomics Data Handling: Global Metabolite Profiling and Potential Biomarker Discovery of Epithelial Ovarian Cancer Prognosis. Metabolomics 2011, 7. 614-622. 

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• 19. Jing Chen, Wenzhao Wang, Shen Lv, Peiyuan Yin, Xinjie Zhao, Xin Lu, Fengxia Zhang, Guowang Xu; Metabonomics Study of Liver Cancer Based on Ultra Performance Liquid Chromatography Coupled to Mass Spectrometry with HILIC and RPLC Separations. Anal. Chim. Acta 2009, 650. 3-9. 

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• 18. Jing Chen, Xinjie Zhao, Jens Fritsche, Peiyuan Yin, Philippe Schmitt-Kopplin, Wenzhao Wang, Xin Lu, Hans-Ulrich Haering, Erwin D. Schleicher, Rainer Lehmann, Guowang Xu; Practical Approach for the Identification and Isomer Elucidation of Biomarkers Detected in a Metabonomic Study for the Discovery of Individuals at Risk for Diabetes by Integrating the Chromatographic and Mass Spectrometric Information. Anal. Chem. 2008, 80. 1280-1289. 
• This article was reported as ““To identify me is to know me” by separationsNOW.com,  John Wiley & Sons, Ltd.

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• 17. Jing Chen, Yuanhong Shan, Qin Yan, Sumin Zhao, Peiyuan Yin, Xinjie Zhao, Xin Lu, Xiaowei Xi, Xiaoping Wan, Guowang Xu; A Metabonomics Approach Based on Liquid Chromatography-Mass Spectrometry: from Metabolic Profiling to Potential Biomarker. Sci. China-Chem. 2009, 39. 1268-1276. 

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• 16. Jing Chen, Yuanhong Shan, Xin Lu, Xiaoping Wan, Guowang Xu; Rapid Quantification of Serum Bile Acid Profiles Based on High Performance Liquid Phase Chromatography-Mass Spectrometry and Its Application in Woman Cervical Cancer. J. Chin. Mass Spectrom. Soc. 2009, 30. 109-110. 

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• 15. Yu Chen, Zhiliang Xu, Hongwei Kong, Nan Chen, Jing Chen, Lina Zhou, Feiling Wang, Yuejiao Dong, Shufa Zheng, Zhenjing Chen, Guowang Xu, Lanjuan Li; Differences Between the Metabolic Profiles of Decompensated and Compensated Cirrhosis Patients with Hepatitis B virus Infections under High-Performance Liquid Chromatography-Mass Spectrometry. Metabolomics 2012, 8. 845-853. 

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• 14. Hongbing He, Xianzhe Shi, Jing Chen, Peng Gao, Yayan Lei, Guowang Xu; Metabonomics Study of Oral Cancer by Using Gas Chromatography-Mass Spectrometry and Liquid Chromatography-Mass Spectrometry. Se Pu 2012, 30. 245-251. 

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• 13. Qiang Huang, Peiyuan Yin, Jing Wang, Jing Chen, Hongwei Kong, Xin Lu, Guowang Xu; Method for Liver Tissue Metabolic Profiling Study and Its Application in Type 2 Diabetic Rats Based on Ultra Performance Liquid Chromatography-Mass Spectrometry. J. Chromatogr. B 2011, 879. 961-967. 

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• 12. Sumin Zhao, Yisheng Wang, Abo Dou, Jing Chen, Xin Lu, Rui Cao, Congjian Xu, Guowang Xu; Study of Phospholipid Profile of Ovarian Tumor by High Performance Liquid Chromatography-Mass Spectrometry. Se Pu 2011, 29. 843-850. 

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• 11. Lina Zhou, Peiyuan Yin, Jing Chen, Xin Lu, Guowang Xu; The Strategy for Structure Identification in Metabonomics Based on LTQ-Orbitraps. J. Chin. Mass Spectrom. Soc. 2010, 31. 338-339. 

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• 10. Xinjie Zhao, Jens Fritsche, Jiangshan Wang, Jing Chen, Kilian Rittig, Philippe Schmitt-Kopplin, Andreas Fritsche, Hans-Ulrich Haering, Erwin D. Schleicher, Guowang Xu, Rainer Lehmann; Metabonomic Fingerprints of Fasting Plasma and Spot Urine Reveal Human Pre-diabetic Metabolic Traits. Metabolomics 2010, 6. 362-374. 

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• 9. Yan Gu, Yifei Zhang, Xianzhe Shi, Xiaoying Li, Jie Hong, Jing Chen, Weiqiong Gu, Xin Lu, Guowang Xu, Guang Ning; Effect of Traditional Chinese Medicine Berberine on Type 2 Diabetes Based on Comprehensive Metabonomics. Talanta 2010, 81. 766-772. 

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• 8. Marianna Lucio, Agnes Fekete, Cora Weigert, Brigitte Waegele, Xinjie Zhao, Jing Chen, Andreas Fritsche, Hans-Ulrich Haering, Erwin D. Schleicher, Guowang Xu, Philippe Schmitt-Kopplin, Rainer Lehmann; Insulin Sensitivity Is Reflected by Characteristic Metabolic Fingerprints-A Fourier Transform Mass Spectrometric Non-Targeted Metabolomics Approach. PloS One 2010, 5. e13317. 

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• 7. Hongbing He, Xianzhe Shi, Jing Chen, Wenzhao Wang, Guowang Xu; The Clinical and Metabonomics Study of Yunnan Baiyao on Experimental Diabetic Periodontitis Rats. Modernization of Traditional Chinese Medicine and Materia Medica-World Science And Technology 2009, 11. 195-200. 

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• 6. Fengxia Zhang, Zhenhua Jia, Peng Gao, Hongwei Kong, Xiang Li, Jing Chen, Qin Yang, Peiyuan Yin, Jiangshan Wang, Xin Lu, Famei Li, Yiling Wu, Guowang Xu; Metabonomics Study of Atherosclerosis Rats by Ultra Fast Liquid Chromatography Coupled with Ion Trap-Time of Flight Mass Spectrometry. Talanta 2009, 79. 836-844. 

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• 5. PeiyuanYin, Dafang Wan, Chunxia Zhao, Jing Chen, Xinjie Zhao, Wenzhao Wang, Xin Lu, Shengli Yang, Jianren Gu, Guowang Xu; A Metabonomic Study of Hepatitis B-Induced Liver Cirrhosis and Hepatocellular Carcinoma by Using RP-LC and HILIC Coupled with Mass Spectrometry. Mol. Biosys. 2009, 5. 868-876. 

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• 4. Lewen Jia, Jing Chen, Peiyuan Yin, Xin Lu, Guowang Xu; Serum Metabonomics Study of Chronic Renal Failure by Ultra Performance Liquid Chromatography Coupled with Q-TOF Mass Spectrometry. Metabolomics 2008, 4. 183-189. 

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• 3. Peiyuan Yin, Patamu Mohemaiti, Jing Chen, Xinji Zhao, Xin Lu, Adilijiang Yimiti, Halmurat Upur, Guowang Xu; Serum Metabolic Profiling of Abnormal Savda by Liquid Chromatography/Mass Spectrometry. J. Chromatogr. B 2008, 871. 322-327. 

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• 2. Xinjie Zhao, Yi Zhang, Xianli Meng, Peiyuan Yin, Chong Deng, Jing Chen, Zhang Wang, Guowang Xu; Effect of a Traditional Chinese Medicine Preparation Xindi Soft Capsule on Rat Model of Acute Blood Stasis: A Urinary Metabonomics Study Based on Liquid Chromatography-Mass Spectrometry.  J. Chromatogr. B 2008, 873. 151-158. 

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• 1. Wenzhao Wang, Xinjie Zhao, Xiang Li, Jing Chen, Fanglou Li, Guowang Xu; Lung Cancer Diagnosis Based on Urinary Modified  Nucleoside Metabolic Profiling. Acta Academ. Med. Sin. 2007, 29. 738-741 

【科研项目】

•  科研基金
• 1. 国家自然科学基金青年基金，2018-2020，在研，主持
• 2. 山东省自然科学基金博士基金，2017-2019，在研，主持
• 3. 江苏省自然科学基金青年项目，2017-2020，在研，主持
• 4. 山东大学基本科研业务费， 2017-2019，在研，主持。

【科研成果】

【联合培养情况】

【拟招收研究生情况】

•  2018年拟招收1名硕士研究生

•  欢迎本科生进入课题组