• 电话:0531-88364464
  • 传真:0531-88564464
  • 地址:
    中国山东省济南市山大南路27号
  • 邮编:250100

导师风采

【个人简介】

  • 马玉道,男,生于1962年,
  • 有机化学研究所教授、博士生指导教师。 
  • 联系电话:88361869,13706416907。
  • E-mail: ydma@sdu.edu.cn 

【学习及工作经历】

  • 1984年毕业于山东大学化学系,获理学学士学位。
  • 1992年毕业于山东大学化学系,获理学硕士学位。
  • 2005年毕业于山东大学化学与化工学院,获理学博士学位。
  • 1984年在山东大学化学系任助教。
  • 1991年在山东大学化学系任讲师。
  • 1996年在山东大学化学院任副教授。
  • 2004年在山东大学化学与化工学院任教授。 

【主讲课程】

  •  有机化学,有机合成化学。
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【研究领域和兴趣】

  • 不对称合成与催化
  • 研究手性配体和金属配合物的合成及其在不对称催化反应中的应用。 
  • 研究手性有机催化剂在不对称反应中的催化应用。
  • 结合手性有机催化剂和过渡金属催化剂的双手性控制的不对称催化反应。
  • 新药的创制研究
  • 利用已上市的药物为先导化合物,通过模拟、合成筛选以期创制一类新药。
  • 利用具有高生物活性的天然产物为先导化合物,经过模拟、合成修饰的方法创制新药。

【主要论著】

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【科研项目】

  • 2014-2017作为主持者,承担国家自然科学基金项目:

    手性[2.2]对环蕃基氮杂环卡宾金属配合物的制备及其催化不对称硼化反应的研究

    2011-2014作为主持者,承担山东省自然科学基金项目:

    面手性卡宾铜催化的不对称硼化反应研究

    2008-2010作为主持者,承担山东省自然科学基金重点项目:

    面手性卡宾配体的设计、合成及其在不对称合成中的应用研究

    2008-2011作为主要参加者,承担国家自然科学基金重点项目:

    苔藓植物中抗真菌耐药有效成分的高通量发现与衍生物制备

    2007-2009作为主持者,承担国家自然科学基金资助项目:

    面手性含氮杂环卡宾配合物的组装和功能性质研究

    2007-2009作为主要参加者,承担国家自然科学基金资助项目:

    新型有机半导体材料在场效应晶体管中的应用

    2005-2006作为主持者,承担国家自然科学基金资助项目:

    手性含氮杂环卡宾分子功能材料的设计、合成和表征

    2003-2006作为主持者,承担山东省科委自然科学基金重点项目:

    具有生物活性的羟基磷灰石纳米材料的制备

    2001-2003作为主要参加者,承担国家自然科学基金资助项目:

    三维纳米结构无机/有机杂合体的组装

    1998-2000作为主要参加者,承担国家自然科学基金资助项目:

    沸石分子筛催化亲核加成反应的研究

    1997-1999作为主要参加者,承担山东省科委资助项目:

    芳环亲电取代反应多相催化剂的研制

    1996-1998作为主要参加者,承担山东省科委资助项目:

    工业酯化反应的多相催化剂

    1996-1997作为主持者,承担济南市科委资助项目:

    热敏传感液的研制

    1996-1998作为主要参加者,承担山东大学资助项目:

    沸石分子筛催化的缩醛化

    1998-1999作为主持者,承担横向项目:

    N-环丙基-1,3,5-三嗪-2,4,6-三胺的合成

    2003-2007作为主持者,承担横向项目:

    吡啶化合物的实验室合成

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【科研成果】

  • 代表性成果:
  • 1. LeiZhao, Yudao Ma*, Fuyan He, Wenzeng Duan, Jianqiang Chen, Chun Song*

    Enantioselectiveβ‑Boration of Acyclic Enones by a [2.2]Paracyclophane-Based N‑HeterocyclicCarbene Copper(I) Catalyst

    TheJournal of Organic Chemistry, 78, 1677-1681, 2013

    2. WenzengDuan, Yudao Ma*, Fuyan He, Lei Zhao, Jianqiang Chen, Chun Song*

    Synthesisof novel planar chiral Ag and Rh N-heterocyclic carbene complexes derived from[2.2]paracyclophane and their application in ultrasound assisted asymmetricaddition reactions of organoboronic acids to aldehydes

    Tetrahedron:Asymmetry, 24, 241-248, 2013

    AsymmetricAddition Reaction of Organoboronic Acids to Aldehydes, Synfacts, 9, 633, 2013

    3.Dengxia Wang, Yudao Ma*, Fuyan He, Wenzeng Duan, Lei Zhao, Chun Song

    Synthesisof Planar Chiral [2.2]Paracyclophanyl Imidazo[1,5-a]pyridinium Salts for the

    Rhodium-CatalyzedAsymmetric Arylation

    Syn.Commun. 43, 810-825, 2013

    4. LeiZhao, Yudao Ma*, Wenzeng Duan, Fuyan He, Jianqiang Chen, Chun Song

    Asymmetricβ‑Boration of α,β-Unsaturated N‑Acyloxazolidinones by [2.2]Paracyclophane-BasedBifunctional Catalyst

    OrganicLetters, 14, 5780-5783, 2012

    Copper-CatalyzedAsymmetric Boration, Synfacts, 9, 163, 2013

    5. FuyanHe, Yudao Ma*, Lei Zhao, Wenzeng Duan, Jianqiang Chen, Chun Song

    PlanarChirality Change in Dediazoniation Reactions of Paracyclophanes and MechanisticImplication

    OrganicLetters, 14, 5436-5439, 2012

    6.Wenzeng Duan, Yudao Ma*, Bo Qu, Lei Zhao, Jianqiang Chen, Chun Song

    Synthesisof new alkoxy/sulfonate-substituted carbene precursors derived from[2.2]paracyclophane and their application in the asymmetric arylation ofaldehydes

    Tetrahedron:Asymmetry, 23, 1369-1375, 2012

    7. FuyanHe, Yudao Ma*, Lei Zhao, Wenzeng Duan, Jianqiang Chen, Zhongxi Zhao

    Synthesisof planar chiral [2.2]paracyclophane Schiff bases for the enantioselectiveHenry reaction

    Tetrahedron:Asymmetry, 23, 809-817, 2012

    8. XiaoLiu, Yudao Ma*, Wenzeng Duan, Fuyan He, Lei Zhao, and Chun Song

    Synthesisof Cyclophanes with Planar and Helical Chirality

    TheJournal of Organic Chemistry, 76, 1953-1956, 2011

    A NewTwist to [2.2]Paracyclophanes, Synfacts, 6, 616, 2011

    9. BingHong, Yudao Ma*, Lei Zhao, Wenzeng Duan, Fuyan He, Chun Song

    Synthesisof planar chiral imidazo[1,5-a]pyridinium saltsbased on [2.2]paracyclophane forasymmetric β-borylation of enones

    Tetrahedron:Asymmetry, 22, 1055-1062, 2011 

    10.QingshuangMa, Yudao Ma*, XiaoLiu, Wenzeng Duan, Bo Qu, Chun Song

    PlanarChiral Imidazolium Salts Based on [2.2]Paracyclophane in the AsymmetricRhodium-Catalyzed 1,2-Addition of Arylboronic Acids to Aldehydes,

    Tetrahedron:Asymmetry, 21, 292-298, 2010

    11.DongyueXin, Yudao Ma*, Fuyan He,

    Synthesisof new planar chiral [2.2]paracyclophane Schiff base ligands and theirapplication in asymmetric Henry reaction,

    Tetrahedron:Asymmetry, 21, 333-338, 2010

    12. BoQu, Yudao Ma*, Qingshuang Ma, Xiao Liu, Fuyan He, and Chun Song*

    AnEfficient Catalyst System for Pd-Catalyzed Amination of [2.2]ParacyclophanylBromides,

    TheJournal of Organic Chemistry 74, 6867-6869, 2009

    13. BinSun, Huiqing Yuan, Guangmin Xi, Yudao Ma*, Hongxiang Lou*

    Synthesisand multidrug resistance reversal activity of dihydroptychantol A and its novelderivatives,

    Bioorganic& Medicinal Chemistry 17, 4981-4989, 2009

    14.Wenzeng Duan, Yudao Ma*, Houqi Xia, Xueying Liu,Qingshuang Ma, Junshan Sun

    Designand Synthesis of Planar Chiral Heterocyclic Carbene Precursors Derived from[2.2]Paracyclophane,

    TheJournal of Organic Chemistry 73, 4330-4333, 2008

    15.Kaiming Wang, Zhengwei Xing, Yudao Ma*, and Qilong Wang

    One-stepPreparation of N-tosylimines Using Zeolite Catalysts,

    CatalysisLetters 123, 129-134, 2008

    16.QiangChai, Chun Song, Zhijun Sun, Yudao Ma*, Changqin Ma,Yong Dai, Merritt B.Andrus*

    Asymmetricallylation of aldehydes with allyltrichlorosilane using aza-paracyclophane-oxazoline-N-oxidecatalysts,

    TetrahedronLetters 47 (48) 8611-8616, 2006

    17. ChunSong, Yudao Ma,* Qiang Chai,Chanqin Ma,Wei Jiang and Merritt B. Andrus*

    Palladiumcatalyzed Suzuki–Miyaura coupling with aryl chlorides using a bulky phenanthrylN-heterocyclic carbene ligand,

    Tetrahedron61, 7438–7446, 2005

    18. ChunSong, Changqin Ma, Yudao Ma,* Wenhua Feng, Shutao Ma, Qiang Chai and Merritt B.Andrus,*

    Bis-paracyclophaneN-heterocyclic carbene-ruthenium catalyzed asymmetric ketone hydrosilylation,

    TetrahedronLetters 46 (18) 3241-3244, 2005

    19. YudaoMa*, Xiaomei Wang, Yong Wang, Yu Feng, and Yunfu Zang;

    Aneconomic approach to chiral thiosulfinates by enantioselective oxidation withhydroperoxide;

    Syn.Communs. 34 (3), 501-507, 2004.

    20. YudaoMa, Chun Song, Changqing Ma, Zhijun Sun, Qiang Chai, and Merritt B. Andrus*

    AsymmetricAddition of Aryl Boron Reagent to Enones with Rhodium Dicyclophane ImidazoliumCarbene,

    Angew.Chem. Int.Ed., 42,5871-5874,2003.

    21. YudaoMa, Chun Song, Wei Jiang, Quansheng Wu, Yong Wang, Xueying Liu, and Merritt B.Andrus*

    SonogashiraCoupling Using Bulky Palladium-Phenanthryl Imidazolium Carbene Catalysis,

    OrganicLetters, 5 (18) 3317-19, 2003.

    22. YudaoMa, Chun Song, Wei Jiang, Guoping Xue, John F. Cannon, Xiaomei Wang, Merritt B.Andrus*

    Borylationof Aryl Diazonium Ions with N-Heterocyclic Carbenes Formed without Added Base,

    OrganicLetters, 5 (24) 4635-4638, 2003.

    23.YudaoMa, Chun Song, Qiang Chai, Changqin Ma, Merritt B. Andrus*

    Palladium-ImidazoliumN-Heterocyclic Carbene-Catalyzed Carbonylative Amidation With Boronic Acids,Aryl Diazonium Ions, and Ammonia,

    Synthesis,18,  2886-2889,  2003.

    24.Merritt B. Andrus*, Yudao Ma, Yunfu Zang and Chun Song

    Pd-ImidazoliumN-HeterocyclicCarbene-CatalyzedCarbonylative Amidation with Boronic Acids,

    TetrahedronLetters, 43, 9137-40, 2002.

    25. YudaoMa, Qilong Wang*, Wei Jiang, Bojun Zuo

    Friedal-Craftsacylation of anisole over zeolite catalysts,

    AppliedCatalysis A:165, 199-206, 1997

    26. YudaoMa, Qilong Wang*, Wei Jiang, Hao Yan, Xingdong Ji, Qin Qiu

    Zeolite-catalyzedesterification, I, synthesis of acetates, benzoates and phthalates,

    AppliedCatalysis A: 139, 51-57, 1996.

    27.QilongWang*, Yudao Ma, Xingdong Ji, Hao Yan, Qin Qiu

    Regioselectiveacylation of anisole with carboxylic acids over HZSM-5 catalyst,

    Chem.Commun., 1995, 2307-2308.

     

【所获专利】

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【联合培养情况】

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【拟招收研究生情况】

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