• 电话:0531-88364464
  • 传真:0531-88564464
  • 地址:
    中国山东省济南市山大南路27号
  • 邮编:250100

导师风采

【个人简介】

  • 郝爱友   教授
  • 山东大学化学与化工学院
  • 男,1966年出生,有机化学研究所博士生导师
  • 电   话:0531-88363306
  • 邮   箱:haoay@sdu.edu.cn
  • 地   址:山东大学(中心校区)化学老楼334室

【学习及工作经历】

  • 2003—至今,山东大学,化学与化工学院,教授,有机化学博士生导师;
  • 2001/9—至今,山东大学,化学与化工学院,教授;
  • 1997/9—2001/9,山东大学,化学院,副教授;
  • 1995/9—1997/9,山东大学,化学与环境学院,讲师;
  • 1992/9—1995/8,中国科学院兰州化学物理研究所,有机化学,博士,导师:金道森,童林荟;
  • 1989/9—1992/7,山东大学,有机化学,硕士,导师:黄慧琴;
  • 1985/9—1989/7,山东师范大学,化学,学士;

【主讲课程】

  •  
  • 有机化学
  • 生物有机化学
  • 有机合成化学
  • 综合化学实验

【研究领域和兴趣】

  •  
  • 超分子化学
  • 功能材料
  • 有机合成
  • 应用化学
  • 环糊精化学
  • 精细化学品化学

【主要论著】

  •  
  • 通讯作者论文
  • 2016年
  • 1. Yajie Wang,† Pengyao Xing,† Shangyang Li,‡ Mingfang Ma,† Minmin Yang,† Yimeng Zhang,† Bo Wang,† and Aiyou Hao*,†, Facile Stimuli-Responsive Transformation of Vesicle to Nanofiber to Supramolecular Gel via ω-Amino Acid-Based Dynamic Covalent Chemistry, Langmuir 2016, 32, 10705−10711
  • 2. Xing Pengyao, Chen Hongzhong, Bai Linyi, Hao Aiyou*, Zhao Yanli*, Superstructure Formation and Topological Evolution Achieved by Self-Organization of a Highly Adaptive Dynamer, ACS Nano, 2016, 10(2): 2716-2727.
  • 3. Xing Pengyao, Zhao Zhuo, Hao Aiyou*, Zhao Yanli*, Tailoring luminescence color conversion via affinitive co-assembly of glutamates appended with pyrene and naphthalene dicarboximide units, Chem Commun (Camb), 2016, 52(6): 1246-1249.
  • 4. Xing Pengyao, Chen Hongzhong, Ma Mingfang, Xu Xingdong, Hao Aiyou*, Zhao Yanli, Light and cucurbit uril complexation dual-responsiveness of a cyanostilbene-based self-assembled system, Nanoscale, 2016, 8(4): 1892-1896.
  • 5. Minmin Yang, Pengyao Xing, Mingfang Ma, Yimeng Zhang, Yajie Wang and Aiyou Hao*, Controlled self-organization of cyanostilbene: emission tuning and photo-responsiveness, Soft Matter, 2016, 12, 6038−6042.
  • 6. Yimeng Zhang, Shangyang Li, Mingfang Ma, Minmin Yang, Yajie Wang, Aiyou Hao* and Pengyao Xing, Tuning of gel morphology with supramolecular chirality amplification using a solvent strategy based on an Fmoc-amino acid building block, New J. Chem., 2016, 40, 5568−5576.
  • 7. Yimeng Zhang, Pengyao Xing, Minmin Yang, Yajie Wang, Bo Wang, Aiyou Hao* and Mingfang Ma, Solvent-polarity-tuned nanostructures assembled from modified octadecylcarbamate with an anthracen moiety, RSC Adv., 2016, 6, 71963−71969.
  • 8. Pengyao Xing,ab Zhuo Zhao,c Aiyou Hao*b and Yanli Zhao*ad, Tailoring luminescence color conversion via affinitive co-assembly of glutamates appended with pyrene and naphthalene dicarboximide units, Chem. Commun., 2016, 52, 1246−1249.
  • 2015年
  • 1. Chu Xiaoxiao, Xing Pengyao, Li Shangyang, Ma Mingfang, Hao Jingcheng, Hao Aiyou*, Dual-tuning multidimensional superstructures based on a T-shaped molecule: vesicle, helix, membraneand nanofiber-constructed gel†, RSC Advances, 2015, (5): 1969-1978.
  • 2. Ma Mingfang, Gu Jinge, Yang Minmin, Li Zhaolou, Lu Zhuoqun, Zhang Yimeng, Xing Pengyao, Li Shangyang, Chu Xiaoxiao, Wang Yajie, Li Qi, Lin Minyan, Hao Aiyou*, Controllable self-assemblies of sodium benzoate in different solventenvironments†, RSC Advances, 2015, (5): 70178-70185.
  • 3. Zhang Hanqiang, Huang Yihong, Huang Qitong, Wei Chan, Zhang Wuxiang, Yang Weize, Dong Peihui, Hao Aiyou*, Hu Shirong*, Self-assembly of graphitic carbon nitride nanosheets–carbon nanotube compositefor
    electrochemical simultaneous determination of catechol and hydroquinone, Electrochimica Acta, 2015, 176: 28-35.
  • 4. Li Shangyang, Zhang Lin, Wang Bo, Ma Mingfang, Xing Pengyao, Chu Xiaoxiao, Zhang Yimeng, Hao Aiyou*, An easy approach for constructing vesicles by using aromatic molecules with beta-cyclodextrin, Soft Matter, 2015, 11(9): 1767-1777.
  • 5. Shirong Hu, Wuxiang Zhang, Jianzhong Zheng, Jiangu Shi, Zhongqiu Lin, Ling Zhong,Guixiang Cai, Chan Wei, Hanqiang Zhang, Aiyou Hao*, One step synthesis cadmium sulphide/reduced graphene oxide sandwiched film modified electrode for simultaneous electrochemical determination of hydroquinone, catechol and resorcinol, RSC Advances, 2015,-(5): 18615-18621.
  • 6. Ma Mingfang, Shang Wenqing, Xing Pengyao, Li Shangyang, Chu Xiaoxiao, Hao Aiyou*, Liu Guangcun, Zhang Yimeng, A supramolecular vesicle of camptothecin for its water dispersion and controllable releasing, Carbohydrate Research, 2015, 402: 208-214.
  • 7. Ma Mingfang, Xu Shengguang, Xing Pengyao, Li Shangyang, Chu Xiaoxiao, Hao Aiyou*, A multistimuli-responsive supramolecular vesicle constructed by cyclodextrins andtyrosine,Colloid and Polymer Science, 2015, 293: 891-900.
  • 8. Zhang Hanqiang, Huang Yihong, Huang Qitong, Wei Chan, Zhang Wuxiang, Kang Lianping, Huang Zhouyi, Hu Shirong*, Hao Aiyou*, Fluorescent probes for “off–on” sensitive and selective detection ofmercury ions and
    L-cysteine based on graphitic carbon nitrid nanosheets†, Journal of Materials Chemistry C, 2015, (3): 2093-2100.
  • 2014年
  • 1. Hou Yuehui, Li Shangyang, Sun Tao, Yang Jingshu, Xing Pengyao, Liu Wenqi, Hao Aiyou*, Organogels based on beta-cyclodextrin system with molecular recognition property, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2014, 80(3-4): 217-224.
  • 2. Xing Pengyao, Chu Xiaoxiao, Ma Mingfang, Li Shangyang, Hao Aiyou*, Melamine as an effective supramolecular modifier and stabilizer in a nanotube-constituted supergel, Chem Asian J, 2014, 9(12): 3440-3450.
  • 3. Chu Xiaoxiao, Xing Pengyao, Li Shangyang, Ma Mingfang, Hao Aiyou*, Inorganic salt-tuned multiple self-assemblies of supramolecular beta-cyclodextrin gel, Colloids and Surfaces A: Physicochemical and Engineering
    Aspects, 2014, 461: 11-17.
  • 4. Ma Mingfang, Sun Tao, Xing Pengyao, Li Zhaolou, Li Shangyang, Su Jie, Chu Xiaoxiao, Hao Aiyou*, A supramolecular curcumin vesicle and its application in controlling curcumin release,Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 459: 157-165.
  • 5. Ma Mingfang, Su Jie, Sheng Xiang, Su Fan, Li Shangyang, Xing Pengyao, Hao Aiyou*, Rapid regio- and enantioselectivities and kinetic resolution of DL-lysine by an effective supramolecular system in water, Journal of Molecular Liquids, 2014, 198: 1-4.
  • 6. Xing Pengyao, Chu Xiaoxiao, Du Guangyan, Ma Mingfang, Li Shangyang, Hao Aiyou*, Utilizing dual responsive supramolecular gel to stabilize grapheme oxidein apolar solvents, Colloid and Polymer Science, 2014, 242: 3223-3231.
  • 7. 马明放,邢鹏遥,李尚洋,初晓晓,王波,郝爱友*,主客体超分子囊泡及其药物载运性能研究,化学进展,2014,(08):1317-1328。
  • 8. Xing Pengyao, Chu Xiaoxiao, Li Shangyang, Ma Mingfang, Hao Aiyou*, Hybrid Gels Assembled from Fmoc-Amino Acid and Graphene Oxide with Controllable Properties, ChemPhysChem, 2014, 15(11): 2377-2385.
  • 9. Li Zhaolou, Hao Aiyou*, Li Xiang, beta-Cyclodextrin supramolecular organogels induced by different carboxylic acids that exhibit diverse morphologies, Journal of Molecular Liquids, 2014, 196: 52-60.
  • 10. Ma Mingfang, Guan Yun, Zhang Cai, Hao Jingcheng, Xing Pengyao, Su Jie, Li Shangyang, Chu Xiaoxiao, Hao Aiyou*, Stimulus-responsive supramolecular vesicles with effective anticancer activity prepared by cyclodextrin and ftorafur, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 454: 38-45.
  • 11. Li Zhaolou, Liu Wenqi, Hao Aiyou*, Gel-sol-gel evolution triggered by formic acid, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 451: 25-32.
  • 12. Hu Shirong, Huang Qitong, Lin Yi, Wei Chan, Zhang Hanqiang, Zhang Wuxiang, Guo Zhenbo, Bao Xiuxiu, Shi Jiangu, Hao Aiyou*, Reduced graphene oxide-carbon dots composite as an enhanced material for electrochemical determination of dopamine, Electrochimica Acta, 2014, 130: 805-809.
  • 13. Hou Yuehui, Sun Tao, Xin Feifei, Xing Pengyao, Li Shangyang, Hao Aiyou*, Transformation from a heat-set organogel to a room-temperature organogel induced by alcohols, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2014, 79(1-2): 133-140.
  • 14. Su Jie, Su Fan, Ma MingFang, Li Shangyang, Xing Pengyao, Hao Aiyou*, Selection of Amino Acids and the Biomimetic Synthesis of Amido Bond in the Presence of beta-CD, Synthetic Communications, 2014, 44(8): 1111-1121.
  • 15. Li Shangyang, Xing Pengyao, Zhang Lin, Xin Feifei, Nie Jinhui, Wang Hailu, Ma Mingfang, Wu Yurong, Hao Aiyou*, Controllable self-assembly of an amphiphilic drug with beta-cyclodextrin and alpha-amylase, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 445: 67-74.
  • 16. Li Zhaolou, Hao Aiyou*, Hao Jingcheng, Formation of heat-triggered supramolecular organogel in which beta-cyclodextrin as sole gelator, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 441: 8-15.
  • 17. Xing Pengyao, Chu Xiaoxiao, Ma Mingfang, Li Shangyang, Zhang Yimeng, Hao Aiyou*, Self- assembly of folic acid/melamine complexes with hierarchy levels: from membranes to porous spherulites and networks, RSC
    Advances, 2014, 4(69): 36633-36639.
  • 18. Xing Pengyao, Chu Xiaoxiao, Ma Mingfang, Li Shangyang, Hao Aiyou*, Supramolecular gel from folic acid with multiple responsiveness, rapid self-recovery and orthogonal self-assemblies, Physical Chemistry Chemical
    Physics, 2014, 16(18): 8346-8359.
  • 19. Ma Mingfang, Xing Pengyao, Xu Shengguang, Li Shangyang, Chu Xiaoxiao, Hao Aiyou*, Reversible pH-responsive helical nanoribbons formed using camptothecin, RSC Advances, 2014, 4(80): 42372-42375.
  • 20. 杨旭,郝爱友*,冯维春,叠氮化钠的水相合成方法及其废液处理,应用化工,2014,(06):1156-1158+1164。
  • 2013年
  • 1. Li Shangyang, Xing Pengyao, Hou Yuehui, Yang Jingshu, Yang Xuezhi, Wang Bo, Hao Aiyou*, Formation of a sheet-like hydrogel from vesicles via precipitates based on an ionic liquid-based surfactant and beta-cyclodextrin, Journal of Molecular Liquids, 2013, 188: 74-80.
  • 2. Li Shangyang, Sun Tao, Yang Xuezhi, Wang Bo, Xing Pengyao, Hou Yuehui, Su Jie, Hao Aiyou*, Light-responsive drug carrier vesicles assembled by cinnamic acid-based peptide, Colloid and Polymer Science, 2013, 291(11): 2639-2646.
  • 3. Li Liuzhong, Wu Yuxiang, Dong Qi, Hao Aiyou*, Cheng Ruihua, Zhong Lei, Liu Boping, Effect of Al-alkyl cocatalyst on ethylene polymerization behavior using silyl chromate (SC)/SiO2 catalyst, Asia-Pacific Journal of Chemical Engineering, 2013, 8(4): 539-546.
  • 4. Tao Sun, Mingfang Ma, Hui Yan, Jian Shen, Jie Su, Aiyou Hao*, Vesicular particles directly assembled from the cyclodextrin/UR-144 supramolecular amphiphiles, Colloids and Surfaces A: Physicochemical and Engineering
    Aspects, 2013, 424: 105-112.
  • 5. Sun Tao, Yan Hui, Xing Pengyao, Su Jie, Li Shangyang, Hao Aiyou*, Cu(II)-triggered release of paclitaxel from a supramolecular complex,SUPRAMOLECULAR CHEMISTRY, 2013, 25(5): 302-309.
  • 6. Pengyao Xing, Tao Sun, Shangyang Li, Aiyou Hao*, Jie Su, Yuehui Hou, An instant-formative heat-set organogel induced by small organic molecules at a high temperature, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2013, 421: 44-50.
  • 7. Xing Pengyao, Li Shangyang, Xin Feifei, Hou Yuehui, Hao Aiyou*, Sun Tao, Su Jie, Multi-responsive supramolecular organogel with a crystalline-like structure, Carbohydr Res, 2013, 367: 18-24.
  • 8. Xin Feifei, Xing Pengyao, Li Shangyang, Hou Yuehui, Hao Aiyou*, A facile method to construct dual-responsive organogels with color changes, RSC Advances, 2013, 3(44): 21959-21963.
  • 9. Xing Pengyao, Chu Xiaoxiao, Li Shangyang, Xin Feifei, Ma Mingfang, Hao Aiyou*, Switchable and orthogonal self-assemblies of anisotropic fibers, New Journal of Chemistry, 2013, 37(12): 3949-3955.
  • 10. Xing Pengyao, Chu Xiaoxiao, Li Shangyang, Hou Yuehui, Ma Mingfang, Yang Jingshu, Hao Aiyou*, Self-recovering beta-cyclodextrin gel controlled by good/poor solvent environments, RSC Advances, 2013, 3(44): 22087-22094.
  • 11. Xing Pengyao, Sun Tao, Hao Aiyou*, Vesicles from supramolecular amphiphiles, RSC Advances, 2013, 3(47): 24776-24793.
  • 12. Xing Pengyao, Chu Xiaoxiao, Du Guangyan, Li Mingzhi, Su Jie, Hao Aiyou*, Hou Yuehui, Li Shangyang, Ma Mingfang, Wu Le, Yu Qiubing, Controllable self-growth of a hydrogel with multiple membranes, RSC ADVANCES, 2013, 3(35): 15237-15244.
  • 第一作者论文
  • 1. 郝爱友,黄惠琴,林吉茂,马晨,利用氯化锌/微孔球状硅胶色谱柱制备α-叔丁基醛酮,有机化学,1999,(04):435-437。
  • 2. 郝爱友,亲核重排反应中氢的迁移能力,化学通报(网络版),1999,-(c00037):1-3。
  • 3. AI-YOU HAO, JI-MAO LIN, LIN-HUI TONG, Selective arylation of β-CD with an ethylenediamino group and characteristics of arylated β-CD dervatives in host-guest complexation, Journal of Inclusion Phenomena and
    Macrocyclic Chemistry, 1999, 34(-): 445-454.
  • 4. Ai You Hao, Lin Hui TONG, Min ZHOU, Selective Modification of -CD on the Secondary Side 4: preparation of arylation of β-CD with a Flexible Chain, Chinese Chemical Letters, 1998, 9(1): 13-16.
  • 5. Ai You HAO, Lin Hui TONG, Tian Lin YANG, Ji Mao LIN, Characteristic Studies of Arylated -Cyclodextrrins in Host-Guest Complexation with Small Molecules, Chinese Chemical Letters, 1998, 9(3): 265-268.
  • 6. 郝爱友,童林荟,环糊精在环境保护中的功能应用,化学试剂,1997,(05):302-303。
  • 7. 郝爱友,童林荟,张复升,光谱活性化环糊精主体与过量客体复合作用性能的简易数学表达式,化学物理学报,1996,(05):450-452。
  • 8. 郝爱友,童林荟,张复升,β-环糊精为TLC流动相添加剂分离对映体,化学通报,1996,(04):16-18。
  • 9. Ai-You HAO, Lin-Hui TONG, Yao-HONG FU, Xia-FEI LAO, Hou-Ming WU, Dimerization constant determination of 6-O-benzoyl-β-CD in aqueous solution, Chinese Chemical Letters, 1996, 7(9): 853-854.
  • 10. Ai You Hao, Lin Hui Tong, Fu Sheng Zhang, Xing Ming Gao, Convenient preparation of monoacylated β-cyclodextrin (cyclomaltoheptaose) on the secondary hydroxyl side, Carbohydrate Research, 1995, 277(2): 333-337.
  • 11. 郝爱友,童林荟,金道森,环糊精的第二面选择性修饰方法新进展,合成化学,1995,-(03):208-214。
  • 12. 郝爱友,童林荟,金道森,2─氧─(2─羟基丙基)─β─环糊精的简便合成及纯化,化学试剂,1995,(03):161-162。
  • 13. 郝爱友,童林荟,张复升,金道森,亲脂类分子增溶剂单2-氧一(2一羟基丙基)一β一环糊精(单2一HP一β一CD)的制备及其NMR表征,合成化学,1995,(04):369-371。
  • 14. 郝爱友,童林荟,高兴明,张复升,β-萘甲酰化β-环糊精的分子识别性能研究,Acta Physico - Chimica Sinica,1995,(03):202-205。
  • 15. Ai-You Hao, Lin-Hui Tong, Fu-Sheng Zhang, Xing-Ming Gao, and Yoshihisa Inoue, Direct TLC sepration of selected six enantiomersof amino-acids using 2-o-[(R) -2-hydroxypropyl]-β-CD as a mobile phase additive, Analytical Letters, 1995, 28(11): 2041-2048.
  • 16. Ai You HAO, Lin Hui TONG, Fu Sheng ZHANG, Dao Sen JIN, A Convenient synthesis of β-cyclodextrion 2- and 3-O-monobenzoate, Chinese Chemical Letters, 1994, 5(8): 645-645.
  • 17. 郝爱友,张立新,张海光,化学滴定法测定羟乙基β-环糊精的平均取代度,应用化学,2002,(03):301-303。
  • 18. 郝爱友,王金山,用环糊精合成楔筒状主体分子新模型,Acta Chimica Sinica,2002,60(8):1536-1538。
  • 19. 郝爱友,王金山,辛志荣,水溶性显色型分子识别器--甲基红基乙二胺基羟丙基-β-环糊精,Acta Chimica Sinica,2002,60(8):1531-1535。
  • 20. Ai You HAO, Jin Shan WANG, The Preparation of 2-O-Acetonyl-β-cyclodextrin as One Key Intermediate for Water Soluble β-Cyclodextrin Derivatives, 中国化学快报(英文版), 2002, 13(9): 832-835.

【科研项目】

  • 1. 山东省科学技术厅,高性能聚甘油脂肪酸酯制备新方法,2012/01-2013/12,已结题,主持;
  • 2. 山东省科学技术厅,强力医药控缓释新材料:含低聚乳酸基团的环糊精衍生物的制备,2003/01-2004/12,已结题,主持;
  • 3. 山东省教育厅,智能提取剂:硅胶载改性环糊精衍生物,2002/01-2003/12,4万元,主持;
  • 4. 国家自然科学基金青年基金,29902004,构筑具有楔形筒状空腔的主体分子新模型,2000/01-2002/12,已结题,主持;
  • 5. 山东省科学技术厅,合成功能性大环分子构筑高性能药用模型,1999/01-2003/12,已结题,主持;
  • 【科研成果】

    •  
    • 已发表论文200余篇及十余项专利
    • 专著:郝爱友,孙昌俊,曲荣军,徐胜广,刘希光,张文志,精编有机化学教程,山东大学出版社,845000字,2009。
    •  

    【所获专利】

    •  
    • 1. 初晓晓,郝爱友,邢鹏遥,一种多重响应的自修复叶酸凝胶及其制备方法,2015.10.28,山东,ZL 2013 1 0595730.6。
    • 2. 邢鹏遥,郝爱友,刘文奇,一种无毒稳定小分子有机凝胶及其制备方法,2013.11.6,山东,ZL 2012 1 082269.X。
    • 3. 李尚洋,苏杰,郝爱友,一种赖氨酸α-氨基的苄氧羰基高效选择性保护方法及其产品,2013.7.3,山东,ZL 2011 1 0422510.4。
    • 4. 邢鹏遥,孙涛,郝爱友,一种负载紫杉醇的囊泡的制备方法,2013.7.3,山东,ZL 2012 1 0082143.2。
    • 5. 郝爱友,孙涛,赵文静,一种二氮喹喔啉类化合物的制备方法,2010.6.9-2029.12.3,山东,ZL 2009 1 0230759.8。
    • 6. 孙涛,郝爱友,一种对1-硝基蒽醌废渣综合利用的方法,2009.3.25-2028.10.15,山东,ZL 2008 1 0157831.4。
    • 7. 郝爱友,申健,低聚乳酸基环糊精衍生物及其制备方法,2005.9.7-2025.2.21,山东,ZL 2005 1 0042460.1。

    【联合培养情况】

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    【拟招收研究生情况】

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    • 每年计划招收2名硕士研究生,1名博士研究生。
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